Ace the Cardiac Vascular Nursing Exam 2025 – Pump Up Your Success!

Question: 1 / 400

Which substance does aldosterone primarily affect?

Chloride reabsorption

Water retention

Sodium and water retention

Aldosterone primarily affects sodium and water retention due to its role as a hormone produced by the adrenal glands. It acts on the distal tubules and collecting ducts of the kidneys, promoting the reabsorption of sodium ions back into the bloodstream. As sodium is reabsorbed, water follows osmotically, resulting in increased water retention. This mechanism is crucial for maintaining blood pressure and fluid balance in the body.

The significance of this function is highlighted in conditions such as heart failure, where fluid overload can lead to symptoms of congestion. In such cases, aldosterone can exacerbate the problem by encouraging further retention of sodium and water, leading to increased blood volume.

While the retention of chloride often accompanies sodium retention, aldosterone directly signals the kidney primarily for sodium absorption. Similarly, while water retention is a consequence of aldosterone’s action, it does so via influences on sodium, not as a primary effect. Magnesium excretion is not directly targeted by aldosterone; instead, aldosterone’s focus is primarily on sodium balance and the resulting water retention that helps regulate blood pressure and volume.

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Magnesium excretion

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